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Kazuwa Nakao Selected Research

RE1-silencing transcription factor

5/2013Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts.
9/2009T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
6/2009Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death.
12/2006Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes.

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Kazuwa Nakao Research Topics

Disease

38Obesity
04/2022 - 01/2002
23Heart Failure
01/2022 - 09/2000
21Body Weight (Weight, Body)
01/2020 - 10/2002
20Fibrosis (Cirrhosis)
01/2020 - 05/2002
19Hypertension (High Blood Pressure)
12/2021 - 09/2000
19Insulin Resistance
01/2017 - 01/2002
15Cardiomegaly (Heart Hypertrophy)
01/2020 - 02/2003
15Neoplasms (Cancer)
01/2016 - 11/2002
13Type 2 Diabetes Mellitus (MODY)
01/2019 - 09/2003
13Diabetic Nephropathies (Diabetic Nephropathy)
01/2017 - 07/2002
13Hypertrophy
12/2013 - 09/2000
12Metabolic Syndrome (Dysmetabolic Syndrome X)
12/2021 - 06/2004
9Osteoporosis
07/2009 - 03/2002
7Diabetes Mellitus
10/2022 - 12/2004
7Chronic Renal Insufficiency
05/2020 - 06/2009
7Hyperglycemia
10/2014 - 09/2003
6Achondroplasia
12/2017 - 12/2003
6Proteinuria
01/2017 - 07/2002
6Ischemia
10/2009 - 03/2003
6Myocardial Infarction
09/2009 - 05/2003
5Inflammation (Inflammations)
01/2020 - 05/2010
5Dyslipidemias (Dyslipidemia)
06/2017 - 06/2004
5Hyperphagia (Overeating)
01/2017 - 03/2006
5Albuminuria
01/2017 - 10/2006
5Sudden Death
01/2016 - 02/2008
5Hyperaldosteronism (Conn Syndrome)
12/2014 - 03/2002
5Adenoma (Adenomas)
12/2014 - 03/2002
5Stroke (Strokes)
09/2008 - 01/2002
4Hypercholesterolemia
01/2018 - 12/2003
4Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
10/2014 - 06/2009
4Non-alcoholic Fatty Liver Disease
05/2014 - 12/2010
4Chronic Kidney Failure (Chronic Renal Failure)
01/2014 - 11/2002
4Fatty Liver
09/2013 - 06/2004
4Cardiovascular Diseases (Cardiovascular Disease)
06/2013 - 08/2002
4Insulinoma
01/2013 - 11/2002
4Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy)
11/2012 - 05/2004
4Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2011 - 10/2008
4Dwarfism
12/2009 - 03/2002
4Weight Gain
12/2009 - 06/2005
4Edema (Dropsy)
08/2007 - 03/2003
3Cardiomyopathies (Cardiomyopathy)
01/2020 - 06/2009
3Left Ventricular Dysfunction
01/2020 - 05/2002
3Diabetic Retinopathy (Retinopathy, Diabetic)
01/2019 - 09/2004
3Glomerulonephritis
01/2017 - 05/2003
3Sclerosis
01/2017 - 02/2008

Drug/Important Bio-Agent (IBA)

28LeptinIBA
04/2022 - 01/2002
22Brain Natriuretic Peptide (Natrecor)FDA Link
10/2022 - 09/2000
18Glucose (Dextrose)FDA LinkGeneric
01/2018 - 01/2002
16Natriuretic PeptidesIBA
01/2020 - 12/2001
16Insulin (Novolin)FDA Link
11/2012 - 01/2002
14Atrial Natriuretic Factor (ANF)IBA
01/2020 - 10/2003
14AldosteroneIBA
01/2020 - 03/2002
14Hormones (Hormone)IBA
11/2012 - 09/2000
12Triglycerides (Triacylglycerol)IBA
12/2021 - 04/2003
11GhrelinIBA
01/2014 - 09/2002
11Angiotensin IIIBA
12/2013 - 12/2001
10Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2003
9LipidsIBA
04/2022 - 05/2002
9Antihypertensive Agents (Antihypertensives)IBA
01/2011 - 02/2008
9candesartanIBA
01/2011 - 02/2008
8Messenger RNA (mRNA)IBA
09/2015 - 05/2003
7GlucocorticoidsIBA
08/2016 - 06/2004
7Hydrocortisone (Cortisol)FDA LinkGeneric
10/2013 - 02/2005
7Amlodipine (Norvasc)FDA LinkGeneric
01/2013 - 02/2008
6CreatinineIBA
01/2016 - 11/2002
6Adrenocorticotropic Hormone (ACTH)FDA Link
12/2014 - 03/2002
6Peptides (Polypeptides)IBA
01/2014 - 10/2002
6Biomarkers (Surrogate Marker)IBA
09/2013 - 01/2007
6atrial natriuretic factor receptor AIBA
10/2009 - 02/2004
5Lipocalin-2IBA
11/2017 - 02/2009
5AlbuminsIBA
01/2017 - 03/2006
5Type 1 Angiotensin ReceptorIBA
01/2016 - 08/2007
5AdrenomedullinIBA
06/2013 - 12/2005
5Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
11/2010 - 01/2002
5EnzymesIBA
04/2010 - 06/2004
5Pioglitazone (Actos)FDA Link
12/2009 - 09/2003
5Transforming Growth Factor beta (TGF-beta)IBA
12/2003 - 09/2000
4Atorvastatin (Lipitor)FDA Link
05/2020 - 02/2007
4Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
01/2020 - 03/2006
4Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2019 - 05/2002
4Connective Tissue Growth FactorIBA
01/2017 - 05/2002
4ReninIBA
01/2016 - 03/2002
4cilnidipineIBA
01/2016 - 01/2011
4LipopolysaccharidesIBA
11/2015 - 12/2003
4CollagenIBA
11/2015 - 06/2005
4Streptozocin (Streptozotocin)FDA Link
10/2014 - 03/2003
4Alanine Transaminase (SGPT)IBA
05/2014 - 12/2010
4RE1-silencing transcription factorIBA
05/2013 - 12/2006
4Guanylate Cyclase (Guanylyl Cyclase)IBA
01/2010 - 06/2005
4Raloxifene Hydrochloride (Evista)FDA Link
03/2008 - 12/2007
4Thyroid HormonesIBA
08/2007 - 03/2002
4Fibronectins (Fibronectin)IBA
07/2002 - 09/2000
3Blood Glucose (Blood Sugar)IBA
12/2021 - 08/2010
3HDL CholesterolIBA
12/2021 - 01/2008
34-nitrophenylphosphorylcholine (NPPC)IBA
12/2017 - 11/2008
3Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA
12/2017 - 01/2004
3des-n-octanoyl ghrelinIBA
01/2017 - 11/2002
3Pharmaceutical PreparationsIBA
10/2016 - 12/2006

Therapy/Procedure

25Therapeutics
01/2020 - 04/2003
5Transplantation
01/2013 - 04/2003